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چکیده
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Abstract,
Recently, the disorder of the hemostasis system in related to the clinical complications from cardiovascular diseases has become more recognized. The stability of the main coagulation and fibrinolysis factors has an important role in maintaining hemostasis. Activation of blood coagulation is associated with accelerated clot formation, whereas activation of blood fibrinolysis increases the breakdown of the blood clot. The effect of hormones and enzymes is a major factor in the fibrinolysis-coagulation balance and imbalance between them, leads to thrombosis. The type, intensity and duration of exercise in the hemostasis process are very important. Most coagulation factors are sensitive to intense exercises. In other hand, Most fibrinolysis factors are susceptible to long-term chronic sub-maximal exercises (over 1 hour) with intensity of 80-75 HR max. It can be concluded that the effect of aerobic exercise on coagulation and fibrinolysis factors has a significant effect when associated with weight loss. In short-term intense exercises, the effect of training on coagulation and fibrinolysis factors has been reported more than aerobic. In concurrent exercise, inter-lukin 1 response decreases, which is associated with the reduction of fibrinogen synthesis. Therefore, the role of intensity is greater than the duration, unless the duration of the training is high.So far, few studies are available related to the influence of exercise on blood coagulation and fibrinolysis and the exact effects of exercise training on the equilibrium between blood coagulation and fibrinolysis is not as yet known. It is necessary to perform different intensity and duration training protocols.
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