مشخصات پژوهش

Abstract Background & Aims: Obesity is a risk factor for the development of cardiovascular diseases, thatit can in part be explain by disturbance in the blood hemostasis. The balance of the coagulation and fibrinolysis factors has an important role in maintaining hemostasis. Thus, the aim of this study was to modulate of blood hemostasis by concurrent training in obese women with low-mobility. Materials & Methods: 20 women (25-30 years, BMI>30 kg/m2) with low mobility were randomly divided in two control and concurrent training groups.Concurrent training performed at 23 minutes sub-maximal aerobic training, two sets with 10 repetitions of 10RM resistance exercise for 8 weeks.Coagulation and fibrinolysis factors measured using the ELISA kits. Analysis of data performed with univariate covariance. Results: In concurrent training fibrinolysis factors includes t-PA (p=0.003), plasminogen and D-dimer (p=0.001) were significantly increased. While, coagulation factors include fibrinogen and PTT significantly increase (p=0.001), but PAI-1 (p=0.003) and PT (p=0.001) significantly decreased. Conclusion:The results of this study showed that fibrinolysis factors most affected by concurrent training because in this type of training, the combination of the effect of aerobic training on plasma volume and resistance training on blood proteins improves fibrinolysis. While further studies on the effect of this type of training on coagulation factors is need.