مشخصات پژوهش

1,4-Dihydropyridin (1,4-DHPs) derivatives containing the 1,4-dihydropyridine structure include calcium antagonists, antitubercular agents, antitumours, bronchodilatings, antidiabetics, antivirals, antianginals and neuropeptide Y Y1 receptor antagonists [1]. Chitosan is actually a heteropolymer containing both glucosamine units and acetylglucosamine units. Among various biopolymers, chitosan based materials have attracted great interest as support for catalytic applications [2]. Herein, we report the utility of heterogeneous, biodegradable, and reusable nano chitosan-VO catalyst for the synthesis of 1,4-dihydropyridine derivatives.